To identify Marburg symptoms, for early onset of signs and symptoms over 2-21 days

Early Marburg symptoms:

Marburg virus disease (MVD), a severe and often fatal illness, begins with sudden symptoms such as fever, chills, headache, and muscle pain (myalgia). By the fifth day, a distinctive maculopapular rash typically appears, especially on the chest, back, and stomach. Other symptoms;

Incubation period

The incubation period of Marburg virus disease (MVD) ranges from 2 to 9 days. During this time, an infected person does not exhibit symptoms and cannot transmit the virus to others. Transmission occurs only after symptoms appear, typically through direct contact with blood, saliva, vomit, urine, feces, or other bodily fluids of an infected individual.

The virus is highly contagious once symptoms develop, requiring close contact for person-to-person spread. In some cases, the virus can persist in bodily fluids, such as semen, for weeks after recovery, posing a risk of delayed transmission even after apparent clinical improvement.

Early Marburg symptoms (before day 5)

  • Fever high
  • Chill
  • Headaches and muscle pains
  • Muscle pain

As the disease progresses, more severe complications arise, including, As the disease progresses, symptoms become more severe, including jaundice, pancreatitis, extreme weight loss, massive bleeding and multi-organ dysfunction. Early recognition of these Marburg disease symptoms is critical for seeking timely supportive care and improving survival chances.

Progressive (after day 5)

  • Maculopapular rash (most prominent on the chest, back, and stomach)
  • Nausea and vomiting
  • Sore throat
  • Chest pain
  • Diarrhoea

Severe Marburg symptoms

  • Jaundice
  • Pancreatic inflammation
  • Significant weight loss
  • Delirium
  • Shock
  • Chest pain
  • Liver failure
  • Severe internal and external bleeding (hemorrhaging)
  • Multi-organ dysfunction

Bottom-line

Marburg virus disease (MVD) has an incubation period of 2 to 21 days, with Marburg virus symptoms typically appearing between 5 to 10 days after exposure. Early symptoms include sudden onset of fever, chills, headache, and muscle aches.

Around the fifth day, a maculopapular rash may develop, primarily on the chest, back, and stomach. As the disease progresses, patients may experience nausea, vomiting, chest pain, sore throat, abdominal pain, and diarrhea.

Severe cases can lead to jaundice, pancreatic inflammation, significant weight loss, delirium, shock, liver failure, massive hemorrhaging, and multi-organ dysfunction. Prompt recognition and supportive care are crucial for improving survival outcomes.

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